Description

1-(5-Bromo-2-Methoxypyridin-3-Yl)Ethanone is a high-purity brominated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures with precision. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the substituted pyridine core.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Chemical Synthesis: A versatile building block for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex aryl groups.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and exploring new chemical spaces.
• Dye & Pigment Industry: Intermediate for synthesizing advanced organic dyes and photostable pigments.

Basic Information

Product Name	1-(5-Bromo-2-Methoxypyridin-3-Yl)Ethanone
CAS No.	1256811-02-5
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	5-Bromo-2-methoxy-3-acetylpyridine; 3-Acetyl-5-bromo-2-methoxypyridine; 1-(5-Bromo-2-methoxy-3-pyridinyl)ethanone; Ethanone, 1-(5-bromo-2-methoxy-3-pyridinyl)-; 5-Bromo-2-methoxypyridin-3-yl methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2-Methoxypyridin-3-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.