Description

2-Bromo-5-Methoxyisonicotinaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of reactive bromine and aldehyde groups on the methoxy-substituted pyridine ring, enabling precise molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A high-value intermediate for custom synthesis houses serving the life sciences sector.

Basic Information

Item	Detail
Product Name	2-Bromo-5-Methoxyisonicotinaldehyde
CAS No.	1256785-15-5
Molecular Formula	C8H6BrNO2
Molecular Weight	230.04 g/mol
Synonyms	5-Methoxy-2-bromoisonicotinaldehyde; 2-Bromo-5-methoxypyridine-4-carboxaldehyde; 4-Formyl-2-bromo-5-methoxypyridine; 2-Bromo-5-methoxy-4-pyridinecarboxaldehyde; Isonicotinaldehyde, 2-bromo-5-methoxy-; (2-Bromo-5-methoxypyridin-4-yl)methanal
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Methoxyisonicotinaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry for comprehensive characterization and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with your specifications. Our quality system supports development from research to commercial scale under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.