Description

2-(2,5-Dibromophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile and stable intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality precursors for drug discovery, ligand synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex, substituted biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific halogenated biaryl structures for enhanced activity.
• Material Science & OLED Development: Serves as a building block for creating organic light-emitting diode (OLED) materials, liquid crystals, and conductive polymers where precise molecular architecture is crucial.
• Ligand & Catalyst Preparation: Employed in the development of novel phosphine or N-heterocyclic carbene (NHC) ligands for asymmetric catalysis and transition metal complexes.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new carbon-carbon bond-forming methodologies and library synthesis for high-throughput screening.
• Fine Chemical Production: Integral to the custom synthesis of specialty chemicals, dyes, and pigments requiring the incorporation of the 2,5-dibromophenyl moiety.

Basic Information

Product Name	2-(2,5-Dibromophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1256781-64-2
Molecular Formula	C12H15BBr2O2
Molecular Weight	353.87 g/mol
Synonyms	2,5-Dibromophenylboronic Acid Pinacol Ester; (2,5-Dibromophenyl)boronic Acid Pinacol Ester; 2,5-Dibromobenzene-1-boronic Acid Pinacol Ester; 2-(2,5-Dibromophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane; 2,5-DibromophenylBPin; Pinacol (2,5-Dibromophenyl)boronate; 1,3,2-Dioxaborolane, 2-(2,5-dibromophenyl)-4,4,5,5-tetramethyl-; 2,5-Dibromobenzene-1-boronic Acid, Pinacol Ester
EINECS	Contact for details

Quality Control

Our 2-(2,5-Dibromophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 11B), HPLC, and GC analysis, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) for long-term storage and during weighing to prevent hydrolysis and maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.