Description

2-Bromo-5-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a building block for creating complex organic molecules used in electronic displays and lighting.
• Polymer & Material Science: Incorporated into specialty polymers and advanced organic frameworks to impart specific electronic or structural properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for methodology development and library synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex intermediates under cGMP conditions where required.

Basic Information

Item	Details
Product Name	2-Bromo-5-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	1256781-58-4
Molecular Formula	C₁₃H₁₈BBrO₃
Molecular Weight	313.00 g/mol
Synonyms	2-Bromo-5-methoxyphenylboronic acid pinacol ester; (2-Bromo-5-methoxyphenyl)boronic acid pinacol ester; 2-Bromo-5-methoxybenzeneboronic acid pinacol ester; 5-Methoxy-2-bromophenylboronic acid pinacol ester; 1,3,2-Benzodioxaborole, 2-(2-bromo-5-methoxyphenyl)-4,4,5,5-tetramethyl-; Pinacol (2-bromo-5-methoxyphenyl)boronate; (5-Methoxy-2-bromophenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Methoxyphenylboronic Acid Pinacol Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) including purity by HPLC/NMR, identity confirmation, and impurity profile is supplied with each shipment. Our quality commitment supports applications from research to commercial-scale cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed under an inert atmosphere to maintain stability and prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.