Description

2-(4-Ethyl-3-Iodophenyl)-2-Methylpropanoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific arylpropanoic acid structure with an iodine substituent. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in areas targeting inflammation, central nervous system (CNS) disorders, and metabolic diseases.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization due to its modifiable ethyl and iodine functional groups.
• API Development: Serves as a crucial building block in the process research and scale-up development of new Active Pharmaceutical Ingredients (APIs).
• Bioconjugation & Probe Synthesis: The iodine atom provides a handle for further functionalization, making it useful in creating molecular probes for biochemical assays and diagnostic applications.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value organic compounds.

Basic Information

Product Name	2-(4-Ethyl-3-Iodophenyl)-2-Methylpropanoic Acid
CAS No.	1256584-73-2
Molecular Formula	C12H15IO2
Molecular Weight	318.15 g/mol
Synonyms	2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid; 2-Methyl-2-(4-ethyl-3-iodophenyl)propanoic acid; α,α-Dimethyl-4-ethyl-3-iodobenzeneacetic acid; 4-Ethyl-3-iodo-α,α-dimethylbenzenecetic acid; 2-(3-Iodo-4-ethylphenyl)-2-methylpropanoic acid; Ibuprofen Iodinated Derivative; Iodo-ethyl Phenyl Isobutyric Acid
EINECS	Contact for details

Quality Control

Our 2-(4-Ethyl-3-Iodophenyl)-2-Methylpropanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.