Description

6-Bromo-7-Methoxy-1,1-Dimethyl-3,4-Dihydronaphthalen-2(1H)-One, CAS NO 1256578-99-0 is a high-purity, synthetically valuable tetralone derivative featuring a bromine substituent, making it a versatile and critical advanced pharmaceutical intermediate (API) and organic building block. Its molecular architecture is specifically designed for complex synthetic transformations, including cross-coupling reactions and further functionalization. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science sectors seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Organic Synthesis Building Block: Utilized in Pd-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex polycyclic structures.
• Agrochemical Research: Acts as a core scaffold for developing new generation herbicides and fungicides with enhanced activity.
• Material Science & OLED Development: Investigated as a starting material for creating organic semiconductors and light-emitting materials.
• Academic & R&D Laboratories: Used in methodological studies and for exploring new synthetic pathways in organic chemistry.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	6-Bromo-7-Methoxy-1,1-Dimethyl-3,4-Dihydronaphthalen-2(1H)-One
CAS No.	1256578-99-0
Molecular Formula	C₁₃H₁₅BrO₂
Molecular Weight	283.16 g/mol
Synonyms	6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one; 6-Bromo-7-methoxy-1,1-dimethyl-1,2,3,4-tetrahydronaphthalen-2-one; 1,1-Dimethyl-6-bromo-7-methoxy-3,4-dihydronaphthalen-2(1H)-one; 2(1H)-Naphthalenone, 6-bromo-7-methoxy-1,1-dimethyl-3,4-dihydro-; Tetralone derivative, brominated; Bromomethoxydimethyltetralone; Advanced Tetralone Intermediate
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-7-Methoxy-1,1-Dimethyl-3,4-Dihydronaphthalen-2(1H)-One is manufactured under strict quality management systems. Our products undergo rigorous quality testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.