Description

6-(4-Ethylpiperazin-1-yl)nicotinaldehyde is a high-purity, advanced pharmaceutical intermediate featuring a strategically functionalized pyridine core. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in hit-to-lead and lead optimization campaigns.
• Kinase Inhibitor Development: The nicotinaldehyde moiety is valuable for creating molecules that interact with kinase enzyme active sites.
• Chemical Biology Probes: Serves as a starting material for synthesizing tool compounds used to study biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of specialized, non-commercial compounds for client projects.

Basic Information

Product Name	6-(4-Ethylpiperazin-1-yl)nicotinaldehyde
CAS No.	1256561-21-3
Molecular Formula	C13H17N3O
Molecular Weight	231.30 g/mol
Synonyms	6-(4-Ethyl-1-piperazinyl)-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 6-(4-ethyl-1-piperazinyl)-; 6-(4-Ethylpiperazin-1-yl)pyridine-3-carbaldehyde; 6-(N-Ethylpiperazinyl)nicotinaldehyde; 1256561-21-3; Aldehyde, 6-(4-ethyl-1-piperazinyl)-3-pyridyl
EINECS	Contact for details

Quality Control

Our 6-(4-Ethylpiperazin-1-yl)nicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.