Description

4,4-Difluoro-1-(Hydroxymethyl)Cyclohexan-1-Ol is a high-value, multi-functional fluorinated cyclohexanol derivative. This compound is a critical building block in advanced organic synthesis, prized for its unique difluoromethylene groups and dual hydroxyl functionality, which enable precise molecular modifications. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in high-performance liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with enhanced chemical resistance and tailored surface properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex, fluorinated organic molecules for various material science applications.
• Fluorine-19 NMR Spectroscopy: Can be utilized as a reference standard or probe in analytical chemistry due to its distinct fluorine signature.

Basic Information

Item	Detail
Product Name	4,4-Difluoro-1-(Hydroxymethyl)Cyclohexan-1-Ol
CAS No.	1256545-48-8
Molecular Formula	C7H12F2O2
Molecular Weight	166.17 g/mol
Synonyms	1-(Hydroxymethyl)-4,4-difluorocyclohexanol; 4,4-Difluoro-1-(hydroxymethyl)cyclohexanol; 4,4-Difluoro-1-hydroxymethyl-1-cyclohexanol; (4,4-Difluorocyclohexyl)methanol (tautomer); 1,1-Bis(hydroxymethyl)-4,4-difluorocyclohexane (possible); Difluorocyclohexanedimethanol (isomer)
EINECS	Contact for details

Quality Control

Every batch of 4,4-Difluoro-1-(Hydroxymethyl)Cyclohexan-1-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your research or production process. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.