Description

1,1-Difluoro-4-Methylenecyclohexane is a highly versatile fluorinated organic building block characterized by its unique difluoromethylene and exocyclic alkene functionalities. This compound is of significant value in advanced organic synthesis, particularly for introducing fluorine atoms and reactive sites into complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for applications ranging from medicinal chemistry to polymer modification.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), especially for introducing fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, coatings, and fluorinated materials with unique surface properties.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions, hydrofluorination, and other cycloaddition or functionalization reactions to construct complex, fluorinated carbo- and heterocycles.
• Liquid Crystal & Electronic Chemical Research: Investigated as a component in the development of fluorinated liquid crystals and dielectric fluids for electronics applications.
• Catalysis & Ligand Development: Utilized to create novel fluorinated ligands for transition metal catalysis, potentially improving catalyst performance and selectivity.

Basic Information

Item	Detail
Product Name	1,1-Difluoro-4-Methylenecyclohexane
CAS No.	1256545-46-6
Molecular Formula	C7H10F2
Molecular Weight	132.15 g/mol
Synonyms	4-Methylenecyclohexylidene Difluoride; 1,1-Difluoro-4-methylidenecyclohexane; 4-Methylene-1,1-difluorocyclohexane; Cyclohexane, 1,1-difluoro-4-methylene-; Difluoro(4-methylenecyclohexylidene)
EINECS	Contact for details

Quality Control

Our 1,1-Difluoro-4-Methylenecyclohexane is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality parameters. Our commitment is to supply material that meets the exacting standards required for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at 2-8°C or as specified on the label. Keep away from heat, sparks, and open flames. Containers should be kept tightly sealed when not in use to prevent evaporation and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.0 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.