Description

1-(4-Chloro-3-Methoxyphenyl)-2,2,2-Trifluoroethanone is a high-purity trifluoromethyl ketone derivative, a key building block in advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the introduction of the trifluoromethyl group into complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced materials with tailored properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the preparation of novel ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Fluorine Chemistry Studies: Acts as a standard or reagent in academic and industrial research focused on fluorination methodologies and the study of fluorine's effects on molecular properties.

Basic Information

Product Name	1-(4-Chloro-3-Methoxyphenyl)-2,2,2-Trifluoroethanone
CAS No.	1256470-62-8
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	4'-Chloro-3'-methoxy-2,2,2-trifluoroacetophenone; 2,2,2-Trifluoro-1-(4-chloro-3-methoxyphenyl)ethanone; 1-(4-Chloro-3-methoxyphenyl)-2,2,2-trifluoroethan-1-one; 4-Chloro-3-methoxy-α,α,α-trifluoroacetophenone; p-Chloro-m-methoxy-α,α,α-trifluoroacetophenone; (4-Chloro-3-methoxyphenyl)(trifluoromethyl)methanone
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-3-Methoxyphenyl)-2,2,2-Trifluoroethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.