Description

Benzoic Acid, 3-(Bromomethyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is a high-value, multi-functional chemical building block that combines a reactive bromomethyl group with a stable boronic ester. This compound matters because it serves as a key intermediate in modern synthetic chemistry, enabling efficient cross-coupling reactions for constructing complex molecules. It is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug candidates, particularly in Suzuki-Miyaura cross-coupling reactions to form biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its boronic ester functionality for molecular diversification.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs or organic photovoltaics, due to its aromatic and functionalizable core.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific, functionalized aromatic compounds.

Basic Information

Item	Detail
Product Name	Benzoic Acid, 3-(Bromomethyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester
CAS No.	1256388-92-7
Molecular Formula	C15H20BBrO4
Molecular Weight	355.04 g/mol
Synonyms	Methyl 3-(Bromomethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 3-Bromomethyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzoic acid methyl ester; Methyl 4-Boronic Acid Pinacol Ester-3-Bromomethyl Benzoate; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(bromomethyl)benzoic Acid Methyl Ester; 3-Bromomethyl-4-(pinacolatoboron)benzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 3-(Bromomethyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures a reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.