Description

n-Isopropyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a high-purity, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group. This compound is a critical building block in modern synthetic chemistry, enabling efficient cross-coupling reactions for the construction of complex molecules. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and materials science industries for the development of new active ingredients and functional materials. The CAS number for this compound is 1256360-63-0.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex biaryl structures, a common motif in drug discovery.
• Pharmaceutical Intermediate: Serves as a versatile building block in the synthesis of potential active pharmaceutical ingredients (APIs), especially those targeting central nervous system and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aromatic amine-boronate architectures.
• Materials Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and organic photovoltaics, where its structure can be incorporated into conjugated polymers.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and labeling strategies due to the reactivity of the boronate ester group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research laboratories for bespoke synthesis projects requiring specific functionalized aniline derivatives.

Basic Information

Product Name	n-Isopropyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	1256360-63-0
Molecular Formula	C15H24BNO2
Molecular Weight	261.17 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(propan-2-yl)aniline; 4-Isopropylaminophenylboronic acid pinacol ester; 4-(Isopropylamino)phenylboronic acid pinacol ester; N-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine; 1-Isopropylamino-4-boronic acid pinacol ester benzene; B-[4-(Isopropylamino)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1256360-63-0
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced intermediates. Every batch is analyzed using modern analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and results from HPLC, NMR, and other relevant tests are available upon request. We adhere to a quality management system to support our customers' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC Area %)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.