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2-(3-Chloro-5-(Methoxymethoxy)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 1256360-44-7


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CAS No.:1256360-44-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(3-Chloro-5-(Methoxymethoxy)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecules in a controlled and selective manner. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to synthesize novel active ingredients and functional organic compounds.

Application

  • Pharmaceutical Intermediate: A key synthon for constructing complex drug candidates, particularly in the synthesis of molecules containing biaryl or substituted phenyl motifs.
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific chlorinated aromatic structures.
  • Material Science Research: Serves as a precursor for organic electronic materials, including polymers and small molecules for OLEDs and organic photovoltaics.
  • Ligand and Catalyst Development: Employed in the creation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
  • Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological pathways and target engagement.
  • Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic routes in laboratory-scale and pilot-scale operations.

Basic Information

Item Details
Product Name 2-(3-Chloro-5-(Methoxymethoxy)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No. 1256360-44-7
Molecular Formula C14H20BClO4
Molecular Weight 298.57 g/mol
Synonyms 3-Chloro-5-(methoxymethoxy)phenylboronic acid pinacol ester; (3-Chloro-5-(methoxymethoxy)phenyl)boronic acid pinacol ester; 2-(3-Chloro-5-(MOMoxy)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane; Pinacol (3-Chloro-5-(methoxymethoxyphenyl)boronate; CAS 1256360-44-7; 3-Chloro-5-MOM-phenylboronic acid pinacol ester
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Quality Control

Every batch of 2-(3-Chloro-5-(Methoxymethoxy)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to cGMP and ISO standards ensures traceability, consistency, and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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