Description

3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is a high-value, protected aniline derivative featuring a pinacol boronate ester group, making it a versatile and critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for drug discovery, catalyst development, and functional polymer synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for compounds requiring aryl-aryl bond formation.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate complex aromatic amine structures.
• Material Science: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs, conductive polymers, and metal-organic frameworks (MOFs).
• Ligand & Catalyst Development: Employed to create novel bidentate or polydentate ligands for transition metal catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology & Proteomics: Utilized as a probe or linker in bioconjugation chemistry and for the development of enzyme inhibitors or molecular imaging agents.
• Academic & Industrial R&D: A fundamental reagent for method development and exploring new synthetic pathways in organic chemistry laboratories worldwide.

Basic Information

Product Name	3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
CAS No.	1256360-31-2
Molecular Formula	C14H22BNO2
Molecular Weight	247.14 g/mol
Synonyms	4-Amino-2,6-dimethylphenylboronic acid pinacol ester; 2,6-Dimethyl-4-aminophenylboronic acid pinacol ester; (4-Amino-2,6-dimethylphenyl)boronic acid pinacol ester; 3,5-Dimethyl-4-(pinacolatoboryl)aniline; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,5-dimethylaniline; 4-Borono-2,6-dimethylaniline pinacol ester; 2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine
EINECS	Contact for details

Quality Control

Our production of 3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting compliance in regulated research and manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.