Description

2-Methyl-1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propan-1-Ol is a high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecular architectures through reliable cross-coupling reactions. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediates: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the boronate moiety facilitates the introduction of complex aryl groups.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized to tag or modify biomolecules for imaging and diagnostic applications due to its reactive handle.
• Fine Chemical Production: Integral for the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	2-Methyl-1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propan-1-Ol
CAS No.	1256360-30-1
Molecular Formula	C16H25BO3
Molecular Weight	276.18 g/mol
Synonyms	2-Methyl-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propan-1-ol; 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2-methylpropan-1-ol; 4-(2-Methyl-1-hydroxypropyl)phenylboronic acid pinacol ester; Pinacol [4-(2-methyl-1-hydroxypropyl)phenyl]boronate; 2-Methyl-1-(4-boronic acid pinacol ester phenyl)propan-1-ol; 4-(1-Hydroxy-2-methylpropyl)phenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Methyl-1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propan-1-Ol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.