Description

2-(3-Methoxy-5-(Methylthio)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient and selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, particularly in the development of new active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of specific aryl groups is required for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for creating sophisticated organic semiconductors and charge-transport materials used in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Polymer and Material Science: Facilitates the incorporation of functional aromatic units into polymers, leading to materials with tailored thermal, optical, or mechanical properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies and complex molecule construction.

Basic Information

Product Name	2-(3-Methoxy-5-(Methylthio)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1256360-25-4
Molecular Formula	C14H21BO3S
Molecular Weight	280.19 g/mol
Synonyms	3-Methoxy-5-(methylthio)benzeneboronic acid pinacol ester; (3-Methoxy-5-(methylthio)phenyl)boronic acid pinacol ester; Pinacol [3-methoxy-5-(methylthio)phenyl]boronate; 5-(Methylthio)-3-methoxyphenylboronic acid pinacol ester; [3-Methoxy-5-(methylsulfanyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-[3-Methoxy-5-(methylthio)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our production of 2-(3-Methoxy-5-(Methylthio)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR (1H and 13C), and GC-MS, to confirm identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening containers to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.