Description

2-(3-Chloro-5-(Methylthio)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile intermediate for constructing complex molecules via cross-coupling reactions, enabling the development of advanced materials and pharmaceuticals. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality organoboron reagents.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific chlorophenyl-thioether motifs.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Diagnostics: Employed in the synthesis of probes and ligands for biochemical assays and diagnostic tools.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CROs and CDMOs specializing in bespoke organic molecule production.

Basic Information

Product Name	2-(3-Chloro-5-(Methylthio)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1256360-24-3
Molecular Formula	C13H18BClO2S
Molecular Weight	284.61 g/mol
Synonyms	3-Chloro-5-(methylthio)benzeneboronic acid pinacol ester; (3-Chloro-5-(methylthio)phenyl)boronic acid pinacol ester; Pinacol [3-chloro-5-(methylsulfanyl)phenyl]boronate; 2-[3-Chloro-5-(methylsulfanyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Chloro-5-methylsulfanylbenzeneboronic acid pinacol ester; CAS 1256360-24-3
EINECS	Contact for details

Quality Control

Our production of 2-(3-Chloro-5-(Methylthio)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.