Description

Benzyl Isopropyl(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Carbamate is a high-value, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound is critical for enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are foundational to modern medicinal chemistry and drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex small molecule therapeutics, agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring biaryl linkages.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable boronic ester precursor for palladium-catalyzed carbon-carbon bond formation, enabling the construction of complex molecular architectures.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop novel therapeutic agents.
• Agrochemical Synthesis: Employed in the research and development of new pesticides and herbicides that require specific aryl-aryl bonds.
• Material Science: A precursor for creating organic electronic materials, polymers, and liquid crystals with tailored properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical and chemical industries in process development and scale-up.

Basic Information

Product Name	Benzyl Isopropyl(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Carbamate
CAS No.	1256360-23-2
Molecular Formula	C24H32BNO4
Molecular Weight	409.33 g/mol
Synonyms	Benzyl N-isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)carbanilate; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(1-methylethyl)benzenamine Benzyl Carbamate; Benzyl (4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)(propan-2-yl)carbamate; Isopropyl(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Carbamic Acid Benzyl Ester; PINACOL (4-(BENZYLOXYCARBONYL)(ISOPROPYL)AMINO)PHENYLBORONATE
EINECS	Contact for details

Quality Control

Our Benzyl Isopropyl(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.