Description

5-Methoxy-2,7-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole is a high-value, multi-functional indole-based boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for oncology and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used to create complex heterocyclic structures found in advanced herbicides, fungicides, and insecticides.
• Material Science & OLED Development: Serves as a building block for organic light-emitting diode (OLED) materials and other functional organic electronic components.
• Polymer Chemistry: Enables the incorporation of indole motifs into specialty polymers and dendrimers with tailored properties.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and labelled compounds for biochemical research and diagnostic applications.
• Academic & Contract Research: A vital reagent for methodological development and complex molecule synthesis in academic and contract research organizations (CROs).

Basic Information

Product Name	5-Methoxy-2,7-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole
CAS No.	1256360-22-1
Molecular Formula	C24H35B2NO5
Molecular Weight	439.16 g/mol
Synonyms	2,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methoxy-1H-indole; 5-Methoxy-2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 1H-Indole, 5-methoxy-2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-Methoxy-2,7-di(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole; 2,7-Bis(pinacolatoboryl)-5-methoxyindole; 5-Methoxyindole-2,7-diboronic acid bis(pinacol) ester
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2,7-Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and light-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.