Description

4-Chloro-2-Fluoro-5-Propoxyphenylboronic Acid, Pinacol Ester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to synthesize novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in drug discovery and development for new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Liquid Crystal & OLED Material Precursor: Serves as a critical intermediate in the manufacture of advanced electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Functional Material Chemistry: Enables the creation of specialty polymers and materials with tailored properties for high-performance applications.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tools for studying biological systems and mechanisms.
• Cross-Coupling Reaction Substrate: A reliable and stable boronic ester reagent for palladium-catalyzed Suzuki-Miyaura cross-coupling reactions with various aryl/heteroaryl halides.

Basic Information

Item	Details
Product Name	4-Chloro-2-Fluoro-5-Propoxyphenylboronic Acid, Pinacol Ester
CAS No.	1256360-18-5
Molecular Formula	C15H21BClFO3
Molecular Weight	314.59 g/mol
Synonyms	4-Chloro-2-fluoro-5-propoxyphenylboronic acid pinacol ester; (4-Chloro-2-fluoro-5-propoxyphenyl)boronic acid pinacol ester; 2-(4-Chloro-2-fluoro-5-propoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Chloro-2-fluoro-5-propoxybenzeneboronic acid pinacol ester; Boronic acid, B-(4-chloro-2-fluoro-5-propoxyphenyl)-, 1,1-dimethylethyl ester; CAS 1256360-18-5
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-Fluoro-5-Propoxyphenylboronic Acid, Pinacol Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.