Description

Phenyl(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrol-1-Yl)Methanone is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules through efficient cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boronic ester reagent for constructing biaryl and heterobiaryl structures in drug discovery.
• Pharmaceutical Intermediate: Used in the synthesis of potential therapeutic compounds, including kinase inhibitors and other small molecule drugs.
• Agrochemical Research: Applied in the development of new active ingredients for crop protection products.
• Material Science: Acts as a precursor for organic electronic materials and functional polymers.
• Chemical Biology: Utilized in the synthesis of probes and ligands for target identification and validation.
• Process Chemistry: Employed in route scouting and scale-up for the commercial manufacturing of complex organic molecules.

Basic Information

Product Name	Phenyl(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrol-1-Yl)Methanone
CAS No.	1256360-12-9
Molecular Formula	C17H22BNO3
Molecular Weight	299.18 g/mol
Synonyms	1-(Benzoyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carbophenone; 1-Benzoyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole; 1H-Pyrrole-1-carboxylic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, phenyl ester; Phenyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate; CAS 1256360-12-9
EINECS	Contact for details

Quality Control

Our Phenyl(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrol-1-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.