Description

1-(Methylsulfonyl)Pyrrole-3-Boronic Acid, Pinacol Ester is a high-value, organoboron building block specifically designed for advanced cross-coupling reactions. This compound is critical for the efficient synthesis of complex heterocyclic molecules, enabling the rapid construction of novel chemical architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-couplings for constructing drug-like molecules containing functionalized pyrrole cores.
• Agrochemical Synthesis: Used in the research and development of novel active ingredients, particularly those requiring complex heterocyclic scaffolds.
• Materials Science Research: Serves as a precursor for creating organic electronic materials, such as conductive polymers or organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Enables the synthesis of labeled compounds or molecular probes for studying biological pathways and target engagement.
• Catalyst Ligand Development: Can be utilized to synthesize novel ligand frameworks for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(Methylsulfonyl)Pyrrole-3-Boronic Acid, Pinacol Ester
CAS No.	1256360-09-4
Molecular Formula	C11H18BNO4S
Molecular Weight	271.14 g/mol
Synonyms	1-(Methylsulfonyl)-1H-pyrrole-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(methylsulfonyl)-1H-pyrrole; 1H-Pyrrole-3-boronic acid, 1-(methylsulfonyl)-, 1,1-dimethylethyl ester; 1-Methanesulfonyl-pyrrole-3-boronic acid pinacol ester; N-Methylsulfonyl-3-pyrroleboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 1-(Methylsulfonyl)Pyrrole-3-Boronic Acid, Pinacol Ester undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of research and development applications. Our quality assurance protocols are designed to support cGMP (current Good Manufacturing Practice) compliance for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.