Description

Isobutyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-1-Carboxylate CAS NO 1256360-08-3 is a high-purity, protected pyrrole boronic ester derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic frameworks. It is essential for researchers and process chemists in pharmaceutical development and agrochemical synthesis who require reliable, high-quality intermediates for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides containing complex pyrrole structures.
• Material Science Research: Serves as a precursor for creating functional organic materials, including organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology: Employed in the synthesis of bioconjugates and molecular probes for target identification and validation studies.
• Catalyst Ligand Development: Utilized to create novel ligands for transition metal catalysts used in fine chemical manufacturing.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and medicinal chemistry within R&D laboratories.

Basic Information

Product Name	Isobutyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-1-Carboxylate
CAS No.	1256360-08-3
Molecular Formula	C15H24BNO4
Molecular Weight	293.17 g/mol
Synonyms	1H-Pyrrole-1-carboxylic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, isobutyl ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylic Acid Isobutyl Ester; Isobutyl 3-(Pinacolatoboryl)-1H-pyrrole-1-carboxylate; 3-Borono-1H-pyrrole-1-carboxylic Acid Isobutyl Ester, Pinacol Ester; 1-(Isobutoxycarbonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole
EINECS	Contact for details

Quality Control

Our Isobutyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-1-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.