Description

Isopropyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-1-Carboxylate is a high-value, protected boronic ester derivative of a pyrrole heterocycle. This compound serves as a critical building block in modern synthetic chemistry, enabling the precise construction of complex molecular architectures. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl and heteroaryl structures prevalent in drug candidates.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing pyrrole or complex aromatic motifs.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides requiring specific heterocyclic frameworks.
• Material Science Research: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Proteomics: Can be utilized in the synthesis of molecular probes and enzyme inhibitors for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	Isopropyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-1-Carboxylate
CAS No.	1256360-07-2
Molecular Formula	C14H24BNO4
Molecular Weight	281.16 g/mol
Synonyms	1H-Pyrrole-1-carboxylic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1-methylethyl ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylic acid isopropyl ester; Isopropyl 3-(pinacolatoboryl)-1H-pyrrole-1-carboxylate; 3-Pinacolatoboryl-1H-pyrrole-1-carboxylic acid isopropyl ester; 1-Isopropoxycarbonyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole
EINECS	Contact for details

Quality Control

Our Isopropyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-1-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to current Good Manufacturing Practice (GMP) principles where applicable. Comprehensive analytical testing, including NMR, HPLC, and mass spectrometry, is performed. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.