Description

Methyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-1-Carboxylate is a high-value, protected pyrrole boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in enabling efficient, palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing functionalized pyrrole or indole cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with complex heterocyclic structures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as conductive polymers and organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for studying biological systems.
• Academic & Contract Research: A vital reagent for methodology development and complex molecule synthesis in university and CRO laboratories.
• Custom Synthesis: Used as a starting material for the contract manufacturing of bespoke fine chemicals and advanced intermediates.

Basic Information

Product Name	Methyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-1-Carboxylate
CAS No.	1256360-05-0
Molecular Formula	C12H20BNO4
Molecular Weight	253.10 g/mol
Synonyms	1H-Pyrrole-1-carboxylic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate; 3-Pinacolboryl-1H-pyrrole-1-carboxylic acid methyl ester; Methyl 3-(pinacolboryl)-1H-pyrrole-1-carboxylate; 1-Carbomethoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole; 3-Boronopyrrole-1-carboxylic acid methyl ester, pinacol ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Due to its hygroscopic and easily oxidized nature, the container should be kept tightly sealed after each use to minimize exposure to moisture and air. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.