Description

1-Boc-7-Methylindole-3-Boronic Acid, Pinacol Ester is a high-purity, protected boronic ester building block essential for modern synthetic chemistry. This compound matters because it provides a stable, reactive handle for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex indole-based molecular architectures. Pharmaceutical, agrochemical, and advanced materials researchers need it for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting CNS disorders and oncology.
• Agrochemical Research: Used to create new indole-derived compounds with potential herbicidal or fungicidal activity.
• Material Science: Enables the synthesis of functionalized indoles for organic electronic materials and advanced polymers.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable boronate reagent for palladium-catalyzed carbon-carbon bond formation with aryl/heteroaryl halides.
• Medicinal Chemistry SAR Studies: Facilitates the rapid exploration of structure-activity relationships by allowing modular introduction of the 7-methylindole moiety.
• Chemical Biology Probe Development: Used to create tagged or modified indole structures for studying biological pathways.

Basic Information

Product Name	1-Boc-7-Methylindole-3-Boronic Acid, Pinacol Ester
CAS No.	1256360-03-8
Molecular Formula	C20H28BNO4
Molecular Weight	357.26 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-7-methyl-1H-indole-3-boronic acid pinacol ester; 7-Methyl-1-Boc-indole-3-boronic acid pinacol ester; tert-Butyl 7-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate; 1-Boc-7-methylindole-3-boronate pinacol ester; 1-Boc-7-Me-indole-3-Bpin; BOC-7-Methylindole-3-Bpin; 1256360-03-8
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized by NMR (1H, 13C), HPLC, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) with full analytical data are available upon request. We adhere to cGMP principles for the production of materials intended for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged manipulations. Keep container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.