Description

Benzyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrimidin-2-Ylcarbamate is a high-value, organoboron-protected pyrimidine derivative, serving as a critical synthetic intermediate in modern organic and medicinal chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise and reliable building blocks are required for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Precursor for creating organic electronic materials, such as OLEDs and semiconductors.
• Chemical Synthesis: Enables Suzuki-Miyaura cross-coupling reactions to form new carbon-carbon bonds in complex molecule assembly.
• Bioconjugation & Probe Development: Utilized in creating labeled compounds and molecular probes for biochemical and diagnostic applications.
• Academic & R&D: Serves as a versatile reagent in university and industrial research laboratories for methodological development and discovery chemistry.

Basic Information

Product Name	Benzyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrimidin-2-Ylcarbamate
CAS No.	1256359-98-4
Molecular Formula	C18H24BN3O4
Molecular Weight	357.21 g/mol
Synonyms	Benzyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)carbamate; 2-Pyrimidinecarbamic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, phenylmethyl ester; Benzyl 5-(pinacolatoboran-2-yl)pyrimidin-2-ylcarbamate; 5-(Pinacolatoboryl)pyrimidin-2-yl benzylcarbamate; Benzyl N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl]carbamate
EINECS	Contact for details

Quality Control

Our Benzyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrimidin-2-Ylcarbamate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems support compliance with global regulatory standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opened for prolonged periods to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.