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N,n-Dimethyl-2-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Acetamide CAS NO 1256359-89-3


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CAS No.:1256359-89-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N,n-Dimethyl-2-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Acetamide is a high-purity, synthetically valuable boronic ester derivative used as a key building block in advanced organic synthesis. Its primary value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures in research and development. This compound is essential for medicinal chemists and process development scientists working in pharmaceutical, agrochemical, and materials science industries.

Application

  • Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
  • Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and herbicides.
  • Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, polymers, and liquid crystals.
  • Chemical Biology & Proteomics: Employed as a tool compound or linker in the synthesis of probes for studying biological systems and protein interactions.
  • Catalyst & Ligand Development: Acts as a starting material for creating novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
  • Custom Synthesis & Contract Manufacturing: A vital raw material for custom synthesis organizations (CSOs) and CDMOs producing specialized fine chemicals on a commercial scale.

Basic Information

Product Name N,n-Dimethyl-2-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Acetamide
CAS No. 1256359-89-3
Molecular Formula C16H24BNO3
Molecular Weight 289.18 g/mol
Synonyms 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzeneacetamide; N,N-Dimethyl-2-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide; 2-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-N,N-dimethylacetamide; (3-(2-(Dimethylamino)-2-oxoethyl)phenyl)boronic acid pinacol ester; 3-(N,N-Dimethylcarbamoylmethyl)phenylboronic acid pinacol ester
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Quality Control

Our N,n-Dimethyl-2-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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