Description

N,n-Dimethyl-2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient, selective carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Serves as a monomer or precursor in the creation of organic semiconductors, OLED materials, and conductive polymers.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies and complex molecule construction.
• Ligand Synthesis: Precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Scale-up Process Chemistry: Suitable for process optimization and pilot-scale synthesis due to its stability and predictable reactivity.

Basic Information

Item	Details
Product Name	N,n-Dimethyl-2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide
CAS No.	1256359-80-4
Molecular Formula	C18H28BNO3
Molecular Weight	317.24 g/mol
Synonyms	4-(2-(Dimethylamino)-2-oxoethyl)phenylboronic acid pinacol ester; 2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-N,N-dimethylacetamide; N,N-Dimethyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide; (4-(2-(Dimethylamino)-2-oxoethyl)phenyl)boronic acid pinacol ester; B-[4-(2-(Dimethylamino)-2-oxoethyl)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of our N,n-Dimethyl-2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetamide undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), identity (NMR, IR), and impurity profiles. Our quality management system is designed to support cGMP and ISO standards for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC Area %)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.