Description

1,2,5-Trimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole is a high-value, organoboron-protected pyrrole derivative, serving as a critical synthetic intermediate. Its core value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, for constructing complex heterocyclic architectures. This compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced materials science, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those containing functionalized pyrrole or indole cores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific heterocyclic motifs.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or emissive layer components in display and lighting technologies.
• Polymer & Material Science: Enables the incorporation of boron-functionalized pyrrole units into conjugated polymers for electronic or sensory applications.
• Ligand & Catalyst Development: Utilized to create novel nitrogen-boron chelating ligands for transition metal catalysis.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Product Name	1,2,5-Trimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole
CAS No.	1256359-32-6
Molecular Formula	C15H26BNO2
Molecular Weight	263.19 g/mol
Synonyms	2-(2,5-Dimethyl-1H-pyrrol-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1,2,5-Trimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,5-trimethylpyrrole; 1,2,5-Trimethylpyrrole-3-boronic acid pinacol ester; N,2,5-Trimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole; Pinacol 1,2,5-trimethyl-1H-pyrrol-3-ylboronate
EINECS	Contact for details

Quality Control

Our production of 1,2,5-Trimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.