Description

1-(Phenylsulfonyl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole is a high-value, multi-functional boronic ester derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used to construct complex heterocyclic scaffolds for developing new-generation pesticides and herbicides with enhanced efficacy.
• Materials Science: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Biology: Acts as a versatile handle for bioconjugation and the development of chemical probes and PROTACs (Proteolysis Targeting Chimeras).
• Academic & Contract Research: Essential for methodology development and exploring new synthetic routes in organic chemistry laboratories worldwide.

Basic Information

Item	Details
Product Name	1-(Phenylsulfonyl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole
CAS No.	1256359-23-5
Molecular Formula	C20H22BNO4S
Molecular Weight	383.27 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(phenylsulfonyl)-1H-indole; 1H-Indole, 1-(phenylsulfonyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1-Benzenesulfonyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole; 1-Phenylsulfonyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(benzenesulfonyl)indole
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent potential degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.