Description

1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propan-1-One is a high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient and selective carbon-carbon bond formation, which is fundamental to constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and functional organic molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a key arylboron reagent for constructing biaryl and heterobiaryl structures prevalent in drug discovery.
• Pharmaceutical Intermediate Synthesis: For the development of novel APIs, especially in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Research: Used in the synthesis of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science & OLED Development: Acts as a precursor for creating organic semiconductors, light-emitting materials, and advanced polymers.
• Ligand and Catalyst Design: Employed in the preparation of novel bidentate ligands for transition metal catalysis.
• Chemical Biology & Probe Development: Useful for labeling and modifying biomolecules in diagnostic and research applications.

Basic Information

Item	Details
Product Name	1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propan-1-One
CAS No.	1256359-22-4
Molecular Formula	C15H21BO3
Molecular Weight	260.14 g/mol
Synonyms	4'-Propionylphenylboronic acid pinacol ester; 1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propan-1-one; 4-Propionylphenylboronic acid pinacol ester; 4-Acetylethylbenzene boronic acid pinacol ester; 1-Propanone, 1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; (4-Propionylphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 1-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propan-1-One is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.