Description

6-Methoxycarbonylindole-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a key building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Used to create complex molecular architectures for new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport molecules, where the indole core offers favorable photophysical properties.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the creation of fluorescent or affinity probes to study biological systems.
• Academic & Contract Research: A valuable reagent for methodology development and exploring new synthetic routes in organic chemistry laboratories worldwide.

Basic Information

Product Name	6-Methoxycarbonylindole-2-Boronic Acid Pinacol Ester
CAS No.	1256359-21-3
Molecular Formula	C₁₆H₂₀BNO₄
Molecular Weight	301.15 g/mol
Synonyms	Methyl 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-6-carboxylate; 6-(Methoxycarbonyl)-1H-indole-2-boronic Acid Pinacol Ester; 1H-Indole-6-carboxylic acid, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; 6-Carbomethoxyindole-2-boronic Acid Pinacol Ester; Methyl 2-(pinacolatoboryl)-1H-indole-6-carboxylate; 2-Borono-6-methoxycarbonylindole Pinacol Ester
EINECS	Contact for details

Quality Control

Our 6-Methoxycarbonylindole-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically verified by HPLC, NMR, and LC-MS. We adhere to relevant industry standards to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated place, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.