Description

4-Cyanopyridine-2-Boronic Acid Pinacol Ester is a high-value, multifunctional boronic ester building block designed for advanced organic synthesis. This compound matters for its critical role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for the efficient development of novel active ingredients, functional polymers, and electronic materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and plant growth regulators requiring specific heterocyclic architectures.
• Material Science: Enables the synthesis of conjugated polymers and organic semiconductors for OLEDs, OFETs, and photovoltaic applications.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized bidentate ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Academic & Contract Research: Essential reagent for methodology development and library synthesis in medicinal and process chemistry.

Basic Information

Product Name	4-Cyanopyridine-2-Boronic Acid Pinacol Ester
CAS No.	1256359-18-8
Molecular Formula	C₁₃H₁₅BN₂O₂
Molecular Weight	242.09 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isonicotinonitrile; 4-Cyano-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Cyanopyridine-2-boronic acid pinacol ester; 2-Pyridineboronic acid, 4-cyano-, pinacol ester; Isonicotinonitrile, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 4-Cyanopyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.