Description

n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanesulfonamide is a high-purity, advanced pharmaceutical intermediate and key building block in organic synthesis. This compound is valued for its unique molecular structure, which combines a protected boronic ester moiety with an ethanesulfonamide group, enabling precise cross-coupling reactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients, particularly in Suzuki-Miyaura coupling reactions.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) for drug discovery and development programs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for constructing complex biaryl and heterobiaryl structures central to many modern therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific aryl-boron functionalities.
• Material Science: A building block for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic research.
• Custom Synthesis: Provides a specialized starting point for contract research organizations (CROs) and fine chemical manufacturers engaged in custom synthesis projects.

Basic Information

Product Name	n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanesulfonamide
CAS No.	1256359-16-6
Molecular Formula	C14H22BNO4S
Molecular Weight	311.21 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-ethylbenzenesulfonamide; 2-[4-(Ethylsulfamoyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; N-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide; B-(4-[(Ethylamino)sulfonyl]phenyl)boronic acid pinacol ester; 1256359-16-6; Ethanesulfonamide, N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-
EINECS	Contact for details

Quality Control

Our n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Ethanesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.