Description

2-(4-(Isopropylsulfonyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science: Serves as a precursor for organic electronic materials, including polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for methodology development and creating complex molecular libraries.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates on a commercial scale.

Basic Information

Product Name	2-(4-(Isopropylsulfonyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1256359-13-3
Molecular Formula	C15H23BO4S
Molecular Weight	310.22 g/mol
Synonyms	4-(Isopropylsulfonyl)phenylboronic acid pinacol ester; 4-(Isopropylsulfonyl)benzeneboronic acid pinacol ester; [4-(Propan-2-ylsulfonyl)phenyl]boronic acid pinacol ester; 2-[4-(1-Methylethylsulfonyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(Isopropylsulfonyl)phenyl-Bpin; CAS 1256359-13-3; (4-Isopropylsulfonylphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of our 2-(4-(Isopropylsulfonyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive coupling reactions. Our quality assurance protocols include HPLC, NMR, and GC-MS analysis to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening containers to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.