Description

n-(Methylsulfonyl)-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanesulfonamide is a high-value, bifunctional chemical intermediate featuring both a sulfonamide and a protected boronic ester group. This compound is critical for enabling advanced cross-coupling reactions, particularly in the synthesis of complex pharmaceutical molecules and organic electronic materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who require precise molecular building blocks for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing sulfonamide pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging the boronic ester functionality for creating diverse biaryl structures.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or host materials in OLED devices due to its rigid, conjugated potential.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis or as a model compound in methodological studies of boron chemistry.
• Polymer Chemistry: Can be incorporated into specialty polymers to impart specific electronic or solubility properties.
• Chemical Biology Probes: Utilized in the synthesis of probes and tags for studying biological processes, where the boronic ester can be further functionalized.

Basic Information

Product Name	n-(Methylsulfonyl)-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanesulfonamide
CAS No.	1256359-12-2
Molecular Formula	C14H22BNO6S2
Molecular Weight	383.27 g/mol
Synonyms	N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-N-(methylsulfonyl)methanesulfonamide; 4-(N-Methanesulfonyl-methanesulfonamido)phenylboronic acid pinacol ester; 1-(Methylsulfonyl)-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanesulfonamide; Bis(methanesulfonyl)(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amine; 1256359-12-2
EINECS	Contact for details

Quality Control

Every batch of n-(Methylsulfonyl)-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanesulfonamide is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (HPLC/NMR), identity confirmation, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize moisture uptake. Optimal storage temperature is between 2°C and 8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.