Description

4-Methyl-2-Nitrophenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its enhanced stability compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific biphenyl or heterobiaryl structures.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as polymers for OLEDs or OFETs.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	4-Methyl-2-Nitrophenylboronic Acid, Pinacol Ester
CAS No.	1256359-10-0
Molecular Formula	C13H18BNO4
Molecular Weight	263.10 g/mol
Synonyms	2-Nitro-4-methylbenzeneboronic Acid Pinacol Ester; 4-Methyl-2-nitrophenylboronic Acid Pinanediol Ester; (4-Methyl-2-nitrophenyl)boronic Acid Pinacol Ester; 2-(4-Methyl-2-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (4-Methyl-2-nitrophenyl)boronate; B-(4-Methyl-2-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Nitrophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.