Description

n-[2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Butan-1-Amine is a high-value, protected boronic ester derivative that serves as a critical synthetic intermediate in modern organic chemistry. Its primary commercial value lies in enabling efficient, high-yield cross-coupling reactions, which are fundamental to constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific aryl-boron functionalities.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and activity-based protein profiling (ABPP) agents due to its reactive boronate group.
• Ligand & Catalyst Development: Utilized for synthesizing novel bidentate or tridentate ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CROs/CMOs serving the global life sciences industry.

Basic Information

Product Name	n-[2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Butan-1-Amine
CAS No.	1256359-08-6
Molecular Formula	C17H28BNO2
Molecular Weight	289.22 g/mol
Synonyms	1-Butanamine, N-[[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]-; N-[(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)]butylamine; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl butylamine; N-Butyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-amine; Pinacol [2-[(Butylamino)methyl]phenyl]boronate; (2-((Butylamino)methyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of n-[2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Butan-1-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All material is characterized by NMR (1H, 13C, 11B), HPLC, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.