Description

2-(4-(Ethylthiomethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters as a versatile intermediate for constructing complex molecules via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced material development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates through palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-boronate functionalities.
• Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other advanced organic electronic components.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Synthesis: Utilized in the creation of molecular probes and bioconjugates for diagnostic and research applications.
• Polymer Chemistry: Acts as a monomer or functionalization agent in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	2-(4-(Ethylthiomethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1256359-06-4
Molecular Formula	C15H23BO2S
Molecular Weight	278.22 g/mol
Synonyms	4-(Ethylthiomethyl)phenylboronic acid pinacol ester; (4-((Ethylthio)methyl)phenyl)boronic acid pinacol ester; 2-[4-(Ethylsulfanylmethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1,3,2-Dioxaborolane, 2-[4-[(ethylthio)methyl]phenyl]-4,4,5,5-tetramethyl-; B-[4-[(Ethylthio)methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-((Ethylthio)methyl)benzeneboronic acid pinacol ester; (4-(Ethylthiomethyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(4-(Ethylthiomethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.