Description

2-Benzyloxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, advanced pharmaceutical intermediate and building block for organic synthesis. This compound is a critical reagent in modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boronic ester pinacol ester reagent for constructing biaryl and heterobiaryl systems, a cornerstone of modern medicinal chemistry.
• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-pyridine motifs.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors, where precise molecular structure is essential.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-Benzyloxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1256359-03-1
Molecular Formula	C18H22BNO3
Molecular Weight	311.19 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(phenylmethoxy)pyridine; 2-(Benzyloxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Benzyloxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(Benzyloxy)-4-(pinacolboryl)pyridine; 4-Pinacolatoboryl-2-benzyloxypyridine; 2-Benzyloxy-4-pyridineboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Benzyloxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance in sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.