Description

5-Methoxycarbonylindole-2-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is critical for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel indole-based drug candidates, including kinase inhibitors and receptor antagonists.
• Suzuki-Miyaura Cross-Coupling: Enables the formation of carbon-carbon bonds for constructing complex biaryl and heterobiaryl structures in medicinal chemistry.
• Agrochemical Research: Used in the development of new crop protection agents and herbicides with specific biological activity.
• Material Science: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Employed in the synthesis of molecular probes and labeled compounds for biochemical research.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis projects.

Basic Information

Product Name	5-Methoxycarbonylindole-2-Boronic Acid Pinacol Ester
CAS No.	1256358-96-9
Molecular Formula	C₁₆H₂₀BNO₄
Molecular Weight	301.15 g/mol
Synonyms	Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-5-carboxylate; 5-(Methoxycarbonyl)-1H-indole-2-boronic acid pinacol ester; 1H-Indole-5-carboxylic acid, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; Methyl 2-(pinacolboranyl)-1H-indole-5-carboxylate; 5-Carbomethoxyindole-2-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 5-Methoxycarbonylindole-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in GMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.