Description

4-Chloroindole-2-Boronic Acid, Pinacol Ester is a high-value, protected boronic acid derivative crucial for modern synthetic organic chemistry. This compound serves as a key synthetic intermediate, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for the development of novel indole-based active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing complex indole derivatives with potential therapeutic activity.
• Suzuki-Miyaura Cross-Coupling: Enables the efficient construction of biaryl and heterobiaryl systems in drug discovery and material science.
• Agrochemical Research: Used in the development of new crop protection agents and herbicides featuring the indole scaffold.
• Material Science: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs) and electronic materials.
• Academic & Contract Research: Essential reagent for methodological development and library synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	4-Chloroindole-2-Boronic Acid, Pinacol Ester
CAS No.	1256358-95-8
Molecular Formula	C14H17BClNO2
Molecular Weight	277.55 g/mol
Synonyms	4-Chloro-1H-indole-2-boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-chloro-1H-indole; 4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 4-Chloroindole-2-boronic acid pinacol ester; 4-Chloro-1H-indole-2-boronic acid, pinacol ester; B-(4-Chloro-1H-indol-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-Chloroindole-2-Boronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.