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2-tert-Butoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine CAS NO 1256358-89-0


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CAS No.:1256358-89-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-tert-Butoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, organoboron building block essential for modern synthetic chemistry. This compound is specifically designed to facilitate the formation of carbon-carbon bonds via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology in pharmaceutical and advanced materials research. It is a critical intermediate for researchers and process chemists in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-purity reagents for constructing complex molecular architectures.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in creating novel pyridine-containing drug candidates.
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that incorporate the pyridine moiety.
  • Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
  • Cross-Coupling Reactions: Primarily employed in Suzuki-Miyaura cross-coupling to introduce the 2-tert-butoxypyridin-4-yl group into target molecules.
  • Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and creating complex organic molecules.
  • Ligand Synthesis: Potential precursor for the development of novel ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name 2-tert-Butoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No. 1256358-89-0
Molecular Formula C15H24BNO3
Molecular Weight 277.17 g/mol
Synonyms 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(tert-butoxy)pyridine; 2-(tert-Butoxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-tert-Butoxypyridine-4-boronic acid pinacol ester; 4-Borono-2-tert-butoxypyridine pinacol ester; Pyridine, 2-(1,1-dimethylethoxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-t-Butoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
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Quality Control

Our 2-tert-Butoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for advanced intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for long-term stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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