Description

4-Methoxy-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds between aromatic rings, a cornerstone of medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the creation of novel pyridine-based ligands for transition metal catalysis.
• Material Science Research: Acts as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized for the synthesis of tagged molecules and probes for studying biological systems and target engagement.

Basic Information

Product Name	4-Methoxy-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1256358-88-9
Molecular Formula	C₁₃H₂₀BNO₃
Molecular Weight	249.11 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methoxypyridine; 4-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Methoxypyridine-2-boronic acid pinacol ester; 2-(4-Methoxypyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Methoxy-2-pyridinylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.