Description

4,4,5,5-Tetramethyl-2-(3-Methyl-5-(Trifluoromethyl)Phenyl)-1,3,2-Dioxaborolane is a high-value, synthetically versatile organoboron reagent, specifically a pinacol boronic ester. Its core value proposition lies in enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures in advanced chemical synthesis. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and materials science industries who require a reliable, high-purity building block for introducing a substituted phenyl moiety into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing a trifluoromethylphenyl group, which is a common pharmacophore.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the specific phenyl-boronate structure is required.
• Material Science & OLED Development: Serves as a precursor for creating advanced organic electronic materials, including charge-transport layers and emitters in OLED devices.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Development: Utilized to create molecular probes and tags for studying biological systems and diagnostic applications.
• Polymer & Specialty Chemical Manufacturing: Acts as a monomer or modifier in the production of high-performance polymers and specialty chemicals with tailored properties.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(3-Methyl-5-(Trifluoromethyl)Phenyl)-1,3,2-Dioxaborolane
CAS No.	1256358-84-5
Molecular Formula	C14H18BF3O2
Molecular Weight	286.10 g/mol
Synonyms	(3-Methyl-5-(trifluoromethyl)phenyl)boronic acid pinacol ester; 2-(3-Methyl-5-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methyl-5-(trifluoromethyl)benzeneboronic acid pinacol ester; Pinacol (3-Methyl-5-(trifluoromethyl)phenyl)boronate; (3-Methyl-5-(Trifluoromethyl)phenyl)BPin; m-Methyl-m-trifluoromethylphenylboronic acid pinacol ester; CAS 1256358-84-5
EINECS	Contact for details

Quality Control

Our production of 4,4,5,5-Tetramethyl-2-(3-Methyl-5-(Trifluoromethyl)Phenyl)-1,3,2-Dioxaborolane adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.