Description

4-(Tetrahydropyran-4-Yloxymethy)Phenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing biaryl motifs common in kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials, polymers, and liquid crystals.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new catalytic processes and organic transformations.
• Suzuki-Miyaura Cross-Coupling: Primarily employed as the boronic acid component in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	4-(Tetrahydropyran-4-Yloxymethy)Phenylboronic Acid
CAS No.	1256358-78-7
Molecular Formula	C13H19BO4
Molecular Weight	250.10 g/mol
Synonyms	4-((Tetrahydro-2H-pyran-4-yloxy)methyl)phenylboronic acid; [4-[(Oxan-4-yloxy)methyl]phenyl]boronic acid; 4-(THP-O-CH2)C6H4B(OH)2; 4-(Tetrahydropyran-4-yloxymethyl)benzeneboronic acid; B-[4-[(Tetrahydro-2H-pyran-4-yloxy)methyl]phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 4-(Tetrahydropyran-4-Yloxymethy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification parameters. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.