Description

1-Benzenesulfonyl-1H-Indole-4-Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its dual functionality, serving as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions and other palladium-catalyzed transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex indole-based scaffolds in drug discovery and development programs.
• Suzuki-Miyaura Cross-Coupling: Used as a boronic acid coupling partner to form carbon-carbon bonds, enabling the synthesis of biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Employed in the research and production of advanced crop protection agents and herbicides.
• Material Science Research: Serves as a precursor for creating organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors due to its reactive boronic acid group.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-Benzenesulfonyl-1H-Indole-4-Boronic Acid
CAS No.	1256358-55-0
Molecular Formula	C14H12BNO4S
Molecular Weight	301.13 g/mol
Synonyms	4-Borono-1-(phenylsulfonyl)-1H-indole; 1H-Indole-4-boronic acid, 1-(phenylsulfonyl)-; 1-(Benzenesulfonyl)-1H-indole-4-boronic acid; 1-(Phenylsulfonyl)-1H-indole-4-boronic Acid; B-[1-(Phenylsulfonyl)-1H-indol-4-yl]boronic acid; 1-Benzenesulfonylindole-4-boronic Acid; 4-Boron-1-(phenylsulfonyl)-1H-indole
EINECS	Contact for details

Quality Control

Our 1-Benzenesulfonyl-1H-Indole-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.