Description

2-(Benzyloxy)Pyridine-4-Boronic Acid is a high-value organoboron building block used in advanced organic synthesis. This compound is critical for facilitating the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and materials chemistry. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates containing biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific pyridine-based structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: Serves as a versatile boronic acid partner in Suzuki-Miyaura cross-coupling with various aryl or vinyl halides to form biaryl linkages.
• Chemical Biology & Medicinal Chemistry: Utilized in the design and synthesis of molecular probes, enzyme inhibitors, and other biologically active compounds.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-(Benzyloxy)Pyridine-4-Boronic Acid
CAS No.	1256355-62-0
Molecular Formula	C₁₂H₁₂BNO₃
Molecular Weight	229.04 g/mol
Synonyms	4-(Benzyloxy)-2-pyridineboronic acid; 2-(Benzyloxy)-4-pyridinylboronic acid; 2-Benzyloxypyridine-4-boronic acid; 4-Pyridineboronic acid, 2-(phenylmethoxy)-; (2-(Benzyloxy)pyridin-4-yl)boronic acid; B-[2-(Phenylmethoxy)-4-pyridinyl]boronic acid; 1256355-62-0
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)Pyridine-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity, keep the container sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.