Description

3-Formylpyridine-4-Boronic Acid is a high-value bifunctional heterocyclic building block, combining a reactive aldehyde group with a versatile boronic acid moiety. This unique structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel drug candidates, chemical probes, and functional materials through cross-coupling and condensation reactions.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic scaffolds.
• Suzuki-Miyaura Cross-Coupling: The boronic acid functionality enables efficient palladium-catalyzed cross-coupling reactions to form biaryl and heterobiaryl structures.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology & Proteomics: Useful for synthesizing affinity probes, activity-based probes, and other tools for target identification and validation.

Basic Information

Product Name	3-Formylpyridine-4-Boronic Acid
CAS No.	1256355-58-4
Molecular Formula	C6H6BNO3
Molecular Weight	150.93 g/mol
Synonyms	4-Formylpyridine-3-boronic acid; (4-Formyl-3-pyridinyl)boronic acid; 3-Pyridinecarboxaldehyde, 4-borono-; 4-Borono-3-pyridinecarboxaldehyde; 3-Formyl-4-pyridinylboronic acid; 4-Pyridylboronic acid-3-carboxaldehyde; PINACOL ESTER OF 3-FORMYLPYRIDINE-4-BORONIC ACID (common derivative)
EINECS	Contact for details

Quality Control

Our 3-Formylpyridine-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Standard Grade), ≥98% (High Purity Grade)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.